As battery technology evolves, the need for precisely-engineered systems that fully harness the potential of active cell materials is becoming increasingly critical. Achieving this requires the design of battery packs that deliver consistent cell performance and seamless integration into vehicles while meeting strict design constraints and upholding the highest standards of safety, reliability, and durability. The architecture of individual cells, including choices around non-active components, significantly influences overall performance and lifespan. Meanwhile, pack-level design introduces complex challenges across thermal, mechanical, and electrical domains often independent of cell chemistry. Optimizing both cell and pack design for specific applications demands a careful balance of factors such as energy density, power output, thermal management, manufacturability, durability, and cost-efficiency.